ETHYL 1H-PYRROLE-2-CARBOXYLATE
Ethyl pyrrole-2-carboxylate
CAS: 2199-43-1
Molecular Formula: C7H9NO2
ETHYL 1H-PYRROLE-2-CARBOXYLATE - Names and Identifiers
| Name | Ethyl pyrrole-2-carboxylate |
| Synonyms | NSC 81360 RARECHEM AL BI 0174 SALOR-INT L305596-1EA Ethyl 2-pyrrolecarboxylate ETHYL PYRROLE-2-CARBOXYLATE Ethyl pyrrole-2-carboxylate ethyl 1H-pyrrole-2-carboxylate ETHYL 1H-PYRROLE-2-CARBOXYLATE Pyrrole-2-carboxylic acid ethyl ester PYRROLE-2-CARBOXYLIC ACID ETHYL ESTER |
| CAS | 2199-43-1 |
| InChI | InChI=1/C7H9NO2/c1-2-10-7(9)6-4-3-5-8-6/h3-5,8H,2H2,1H3 |
ETHYL 1H-PYRROLE-2-CARBOXYLATE - Physico-chemical Properties
| Molecular Formula | C7H9NO2 |
| Molar Mass | 139.15 |
| Density | 1.139±0.06 g/cm3(Predicted) |
| Melting Point | 37-39°C |
| Boling Point | 70°C 0,8mm |
| Flash Point | 70°C/0.8mm |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.0302mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Yellow to Orange |
| BRN | 2645 |
| pKa | 15.25±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.519 |
ETHYL 1H-PYRROLE-2-CARBOXYLATE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 41 - Risk of serious damage to eyes |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| Hazard Class | IRRITANT |
ETHYL 1H-PYRROLE-2-CARBOXYLATE - Reference Information
| Use | Ethyl pyrrole-2-carboxylate is used as a standard substance for chromatographic analysis, and is also used in organic synthesis and pharmaceutical industries. Mainly used as solvent for polyester fiber spinning. Ethyl pyrrole-2-carboxylate is also commonly used as metal preservatives, epoxy resin curing agents, catalysts for olefin polymerization, and raw materials for the pharmaceutical industry. It is also used as a photosensitizer. |
| synthesis method | the preparation method of ethyl pyrrole -2-carboxylate is as follows: 2,2,2-trichloro -1-(1H-pyrrole -2-yl)-ethanone (25g,0.12mol) ethanol solution (200 mL) is treated with potassium carbonate (5g). The mixture is then heated to reflux for 1 hour. After this, the solid residue is filtered out and the solution is concentrated under reduced pressure. Ethyl acetate (200 mL) was added and washed with water (2 ×). The organic phase was dried on Na2SO4. Light yellow solid ethyl pyrrole-2-carboxylic acid (18g). HPLC (method 2):m/z 140.12[m H] ,1H NMR(400.5 MHz,DMSO-d6)δ ppm 1.29(t,J = 7.0Hz,3H),4.23(q,J = 700Hz,2H),6.25-6.04(m,1H),6.86-6.65(m,2H). Tulopyrrole-2-carboxylic acid ethyl ester synthesis route |
Last Update：2024-04-09 20:48:19
